Study Shows Nasal Spray Reduces Brain Inflammation and Supports Memory in Mice

Tue, 21 Apr 2026 09:14:00 +0200

A recent study explores a promising approach to addressing age-related brain decline using a nasal spray. Researchers found that tiny particles released by stem cells, delivered through the nose, can reduce inflammation in the hippocampus, the brain area responsible for learning and memory. This treatment also supports healthier brain cell activity by regulating microRNAs, which act as master switches for gene and signaling pathways. Additionally, the therapy helps restore mitochondrial function, improving energy production in neurons. In experiments with middle-aged mice, treated animals showed improved memory performance, better recognition of objects, and heightened awareness of environmental changes. Both male and female mice responded similarly, suggesting the therapy could be broadly effective. While these results are limited to animal studies, the findings point to a potentially simpler and less invasive alternative to current treatments for cognitive decline and dementia. Resea